

MLB Prop Bets: Chicago White Sox vs St. Louis Cardinals (June 18, 2025)
The St. Louis Cardinals (38-35) face the Chicago White Sox (23-50) at Rate Field on Wednesday at 7:40pm (ET). Let's take a look at the MLB Prop Bets for the matchup. Sonny Gray is the probable pitcher for the Cardinals, while Sean Burke is the probable pitcher for the White Sox. The Cardinals are favored to win at -195, while the White Sox are at +156. The total runs line is set at 8.5, with OVER at -108 and UNDER at -113.
- The Cardinals (-115) have a 40-33 Run Line record this season, while the White Sox (-107) hold a record of 42-31.
- The Cardinals have a 39-32-2 O/U record this season (meaning 39 games have gone over the total runs line, 32 have gone under and two have resulted in a push). The White Sox have a 34-35-4 O/U record.
Scoring Insights
- The Cardinals are averaging 4.7 runs per game this season (9th in the league). Comparatively, the White Sox are averaging only 3.4 (28th).
- In the field, the Cardinals are allowing 4.3 runs per game this season (18th in the league), while the White Sox are allowing an average of 4.4 runs (20th).
Let's take a look at how these teams perform in some other key statistical areas.
Batting Insights:
Batting Average
- Looking at their batting averages this season, the Cardinals are at an impressive .257 (ranking 3rd in the Major leagues), while the White Sox are batting an underwhelming .222 (30th).
Home Runs
- In terms of total home runs this season, the White Sox have hit 55 (28th in the Major Leagues). Meanwhile, the Cardinals have managed 68 (24th).
Runs Batted In
- Finally, looking at their runs batted in, the Cardinals have recorded 322 RBIs to rank 10th in the MLB this season. Comparatively, the White Sox have recorded 240 RBIs to rank 28th.
Pitching Insights:
Earned Run Average
- The White Sox have an earned run average of 4.23 this season (23rd in the Majors), while The Cardinals have an ERA of 3.97 (19th).
Strikeouts
- Turning our attention to total strikeouts, the Cardinals have recorded 521 this season, ranking 29th in the MLB. Meanwhile, the White Sox rank 28th for total strikeouts, recording 526.
Opponent Batting Average
- Opponents are batting an average of .255 against the White Sox this season (24th in the Major Leagues). Comparatively, the Cardinals' opponents are at .254 (23rd).
First Innings Moneyline
- Here are their first innings moneyline records in 2025.
Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
---|---|---|---|---|---|---|---|
Cardinals | 16-21-36 | 7-14-15 | 9-7-21 | 6-11-12 | 10-10-24 | 0-0-0 | 2-3-5 |
White Sox | 14-21-38 | 8-8-19 | 6-13-19 | 1-0-0 | 13-21-38 | 0-0-0 | 2-2-6 |
Lead After Three Innings
The Cardinals are -167 to lead after three innings, while the White Sox are +130.
- Here are their records after the first three innings in 2025.
Total | Home | Road | Favorite | Underdog | Neutral | Last 10 | |
---|---|---|---|---|---|---|---|
Cardinals | 25-23-25 | 11-11-14 | 14-12-11 | 12-11-6 | 13-12-19 | 0-0-0 | 2-4-4 |
White Sox | 22-33-18 | 16-12-7 | 6-21-11 | 1-0-0 | 21-33-18 | 0-0-0 | 3-6-1 |
NRFI/YRFI
The NRFI market is paying -125 and the YRFI is paying -106.
- The NRFI is 35-38 in Cardinals games this season. The White Sox also have a 35-38 NRFI record.
Last Time They Met
The Cardinals recorded a lopsided 12-2 victory against the White Sox at Rate Field yesterday. Alec Burleson dominated at the plate in that matchup, notching 1 home run, 2 singles and 2 RBIs. The Cardinals have now won three straight at Rate Field against the White Sox.